How does it work and how is it different from conventional phototherapies? Professor Matthias Born, Director of Clinical and Scientific Affairs at Philips Light & Health, shares key insights on the blue LED light therapy and proof that it can be an effective way for patients to gain relief from psoriasis symptoms.
Studies reveal that blue light reduces the accelerated proliferation of keratinocytes and decreases the inflammatory response.1,2 After long years of research and optimization, Philips Light & Health and its clinical and academic partners have successfully defined the optimal wavelength, intensity and LED settings to harness these properties for the treatment of psoriasis vulgaris.
In an initial clinical study at the University Hospital Aachen in 2009, 40 patients with mild to moderate psoriasis vulgaris used blue LED light therapy (453 nm) for four weeks. It was found that exposure to blue LED light resulted in significant improvement of psoriasis plaques.3 In a second clinical study, 47 patients with mild to moderate psoriasis vulgaris performed blue LED light therapy at home for three months. Daily treatment (5–7 treatments
per week) was carried out for the first four weeks only, followed by three treatments per week for the next eight weeks. No treatment was carried out during the four-week follow-up phase. Compared to the untreated control plaque, therapy with high-intensity blue light resulted in a highly significant reduction of the LPSI (Local Psoriasis Severity Index). 84 % of patients showed an improvement in plaque symptoms (thickness, redness and scaling) compared to baseline. In some patients, complete clearance of the plaque was observed. During the treatment-free follow-up phase, plaque symptoms improved slighlty further, rather than worsened.4
Treatment compliance was excellent: 98% of the patients followed the treatment procedure with blue LED light. 83% of the patients rated the
usability and comfort of the therapy device as ideal or excellent. No adverse events associated with the blue LED light therapy were observed.4
Philips BlueControl is a convenient, UV-free phototherapy for exceptional
Compliance. The device is wearable and enables patients to benefit from blue
light therapy while following their normal daily routines. An easily adjustable textile fixation strap ensures the device fits securely on the extremities. A daily treatment per plaque is recommended. After 30 minutes’ treatment per plaque, the device shuts off automatically. No UV radiation or chemicals are involved, and no adverse effects have been observed. Patients confirm that Philips BlueControl fits right into their daily routine – for exceptional
treatment compliance, and better outcomes.
Philips BlueControl is a Medical device class IIa (CE0344) for the treatment of mild to moderate psoriasis vulgaris. The product is not FDA approved and not available for purchase in the USA. Before altering or stopping any prescribed medication or using the device, patients should consult with their physician and carefully read the
instructions for use. October 2016.
1 Liebmann J, Born M, Kolb-Bachofen MV. Blue-Light Irradiation Regulates Proliferation and Differentiation in Human Skin Cells.
Journal of Investigative Dermatology. 2010; 130: 259-269.
2 Fischer M et al. Blue light irradiation suppresses dendritic cells activation in vitro. Experimental Dermatology. 2013; 22: 554-563.
3 Weinstabl A et al. Prospective randomized study on the efficacy of blue light in the treatment of psoriasis vulgaris. Dermatology.
2011; 223(3): 251-9.
4 Pfaff S et al. Prospective Randomized Long-Term Study on the Efficacy and Safety of UV-Free Blue Light for Treating Mild Psoriasis Vulgaris.
Dermatology. 2015; 231: 24-34.
Philips BlueControl is an EU CE-marked class IIa medical device (CE0344) for the treatment of mild to moderate plaque psoriasis (psoriasis vulgaris). The
device is currently not available outside EU. Before altering or stopping any prescribed medication or using the device, patients should consult with their physicians and carefully read the instructions for use. July 2017.
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